Update Course Rewind: Massive Transfusion Protocol 2023
After 20 ml/kg of blood within an hour, you should activate the MTP according to the MATIC trial investigators
Host summaryKatie Russell summarizing the discussion — not the host's own clinical position2:34 ↗
There is adult data to support starting with FFP in trauma resuscitation
clinicalMeera Kotagal1:17 ↗
The best definition for massive transfusion in kids is 40 ml/kg of any blood product over 24 hours
guidelineMeera Kotagal3:50 ↗
Activating MTP threshold is different than the definition of massive transfusion
clinicalMeera Kotagal3:50 ↗
The more fresh frozen plasma (FFP) you give, the lower your mortality is in balanced resuscitation
Host summaryMeera Kotagal summarizing the discussion — not the host's own clinical position4:40 ↗
The closer you are to 1:1:1 ratio is better and this has been shown in kids, not just adult data
Host summaryMeera Kotagal summarizing the discussion — not the host's own clinical position4:40 ↗
There is great pediatric data on whole blood for trauma resuscitation
clinicalMeera Kotagal4:40 ↗
Kids bleed whole blood, making balanced resuscitation important
clinicalMeera Kotagal4:40 ↗
Blood can usually be returned to the blood bank unless you spike the bag
clinicalMeera Kotagal3:00 ↗
Most trauma coolers that come to the bay do not have platelets initially
clinicalKatie Russell3:28 ↗
After implementing an MTP team, balanced resuscitation rates improved from 25% to 85%
epidemiologicalKatie Russell6:01 ↗
Pre-hospital transfusion could reduce mortality according to recent data
clinical6:23 ↗
There is evidence to support pre-hospital TXA use
clinicalKatie Russell7:32 ↗
Using TXA in MTP should be combined with rapid viscoelastic testing (ROTEM or TEG) to directly target resuscitation goals
clinicalKatie Russell7:32 ↗
Whole blood for pediatric trauma needs to be irradiated, which creates blood bank implementation challenges
clinicalMeera Kotagal3:00 ↗
The MTP team consists of a trauma APP running the team and an ER nurse who knows how to run the Belmont rapid infuser
clinicalKatie Russell5:35 ↗
Update Course Rewind: Updates in Solid Organ Injury Management 2023
APSA guidelines include four basic categories for solid organ injury management: where patients should be admitted, procedures, when to discharge them, and what to do after discharge.
guideline1:45 ↗
In kids, the data doesn't support the need for angioembolization, even if you see active arterial extravasation on CT.
clinical2:10 ↗
APSA guidelines indicate discharge when patients are clinically doing well, with no indication for repeat imaging after discharge.
guideline2:25 ↗
Activity restrictions have moved towards shorter duration; previously grade 4 spleen lacerations required 12 weeks or longer out of activity.
guideline2:45 ↗
Cincinnati Children's Hospital guideline states only hemodynamically abnormal patients go to the ICU.
guideline3:44 ↗
Cincinnati has started discharging isolated grade 1 or 2 splenic injuries from the emergency department.
clinical3:44 ↗
In a study of grade 1 and 2 injuries with no other major organ injured, not a single patient got an intervention during hospitalization, including transfusion.
epidemiological4:00 ↗
Grade 1-2 injuries are discharged from ED if patients are watched for 4 hours and able to tolerate a PO challenge.
clinical4:00 ↗
CT scanning serves two purposes: making a diagnosis overall and determining appropriate discharge activity restrictions, which differ between splenic laceration and small bowel contusion.
clinical4:55 ↗
In the blunt abdominal trauma guideline at Cincinnati, not all patients are scanned; AST and lipase are used to decide who needs a scan.
clinical5:37 ↗
Standardized discharge instructions are created and given to all patients in collaboration with the emergency department.
clinical6:42 ↗
Every patient discharged with solid organ injury is seen in trauma clinic within the week to ensure the child is doing well and to provide continued counseling about activity restrictions.
clinical6:42 ↗
At the Utah practice, 80% of pediatric trauma patients are transfers and most have already had a CBC at the referring hospital.
epidemiological7:17 ↗
For hemodynamically normal children with solid organ injury going to the floor, CBC is not repeated.
clinical7:39 ↗