Pediatric chest wall reconstruction for osteosarcoma: case-based approach
The team has about 10 years of experience with chest wall reconstructions.
clinicalMargaret Mutch0:16 ↗
The patient had an incomplete cord injury with absent lower limb reflexes and altered motor and sensation below the level of T6.
clinicalMargaret Mutch0:27 ↗
The patient underwent emergency posterior laminectomy and partial tumor debulking between the levels of T3 and T7 for cord decompression.
clinicalMargaret Mutch0:42 ↗
Radio guided occult lesion localization using technetium 99 was performed.
Host summaryLizzy Lee summarizes what Dr. Margaret Mutch said — not the host's own clinical position1:12 ↗
Anterior thoracotomy removed a PET avid lesion that confirmed aggressive osteosarcoma replacing a lymph node.
clinicalMargaret Mutch1:17 ↗
Most of the reconstruction needs to be tailored to the needs of each individual, location and size of defects.
opinionMargaret Mutch1:32 ↗
There is a lack of clear evidence-based guidelines for reconstructive materials.
Host summaryLizzy Lee summarizes what Dr. Margaret Mutch said — not the host's own clinical position1:45 ↗
The priority for reconstruction is long-term durability, aesthetics, function, and accommodating future growth.
Host summaryLizzy Lee summarizes what Dr. Margaret Mutch said — not the host's own clinical position1:45 ↗
A lot of the literature on chest wall reconstruction is coming from adults.
clinicalMargaret Mutch1:55 ↗
Spinal surgeons removed all vertebral bodies between T4 and T7 and inserted a cage, and the thoracic team resected ribs 4 to 7.
clinicalMargaret Mutch2:06 ↗
During surgery, a tumor thrombus was found in the azygos which extended into the SVC.
clinicalMargaret Mutch2:28 ↗
The team tends to use resorbable and biosynthetic materials to do the reconstruction.
clinicalMargaret Mutch2:44 ↗
Two systems are available in Australia for resorbable plates: one by Stryker and one by KLS.
clinicalMargaret Mutch2:51 ↗
Instead of using screws packaged with the plates, they used a K-wire drill to drill through the remaining ribs and proline sutures to secure the implant.
Host summaryLizzy Lee summarizes what Dr. Margaret Mutch said — not the host's own clinical position3:05 ↗
Permacol was placed on top of the implant, and a latissimus dorsi pedicled flap was used to cover the Permacol.
clinicalMargaret Mutch3:14 ↗
Permacol is made of a porcine dermal collagen matrix.
clinicalMargaret Mutch3:29 ↗
The delta plates or sonic weld system are polylactide and polyglycolide and polydioxanone plates.
clinicalMargaret Mutch3:32 ↗
The resorbable plates have a strength of 78% at 2 months and 50% at 6 months.
clinicalMargaret Mutch3:47 ↗
The patient had a relapse 18 months following the surgery close to his sternum.
clinicalMargaret Mutch4:05 ↗
Dr. Matt Nartin performed further chest wall reconstruction excising the entire sternum, costochondral cartilages, and anterior ribs and replaced it with a cement mesh.
Host summaryLizzy Lee summarizes what Dr. Margaret Mutch said — not the host's own clinical position4:12 ↗
The patient is currently having adjuvant chemotherapy.
clinicalMargaret Mutch4:22 ↗
There was early postoperative infection in one patient which was treated with IV antibiotics.
clinicalMargaret Mutch4:31 ↗
There were sterile seromas in two patients in the early stages, one at 2 months and one at 8 months.
clinicalMargaret Mutch4:36 ↗
Both patients with sterile seromas were treated with IR drainage.
Host summaryLizzy Lee summarizes what Dr. Margaret Mutch said — not the host's own clinical position4:42 ↗
There was one case of minor scoliosis on follow-up, which is being followed by the spinal team and so far has not needed intervention.
Host summaryLizzy Lee summarizes what Dr. Margaret Mutch said — not the host's own clinical position4:45 ↗
Chest wall reconstruction in children is a complex procedure and should be tailored to the individual patient.
Host summaryLizzy Lee summarizes what Dr. Margaret Mutch said — not the host's own clinical position4:52 ↗
Bioengineering of tissue replacement and 3D printing may be the way of the future in chest wall reconstructions.
Host summaryLizzy Lee summarizes what Dr. Margaret Mutch said — not the host's own clinical position5:17 ↗
Pediatric oncofertility: preserving reproductive futures for childhood cancer survivors
Cancer treatments can cause gonadal failure, limiting or destroying the patient's ability to produce offspring in the future
Host summaryThe host summarizes what Dr. Monica Laronda said — not the host's own clinical position0:53 ↗
Loss of control over reproductive future is one of the top quality of life parameters of importance for childhood cancer survivors
clinicalMonica Laronda1:10 ↗
Most cancer survivors prefer to have a biological offspring over a gamete donation or a gestational carrier
epidemiologicalMonica Laronda1:23 ↗