# Intestinal Organoid Science & Bioengineering — GCMD Library living collection

Updated: n/a · 49 episodes · 0 cited statements

## Episodes
### Organoid Development & Production
- [Scientists Unlock Scalable Production of Human Gut Organoids with Functional Nerves](https://library.globalcastmd.com/watch/scientists-unlock-scalable-production-of-human-gut-organoids-with-functional-ner-16340) — article · [machine version](https://library.globalcastmd.com/watch/scientists-unlock-scalable-production-of-human-gut-organoids-with-functional-ner-16340.md)
- [Intestinal Organoids Help Heal the Gut After Injuries](https://library.globalcastmd.com/watch/intestinal-organoids-help-heal-the-gut-after-injuries-16341) — article · [machine version](https://library.globalcastmd.com/watch/intestinal-organoids-help-heal-the-gut-after-injuries-16341.md)
- [Building and regenerating intestines by manipulating intestinal stem cells](https://library.globalcastmd.com/watch/building-and-regenerating-intestines-by-manipulating-intestinal-stem-cells-16342) — article · [machine version](https://library.globalcastmd.com/watch/building-and-regenerating-intestines-by-manipulating-intestinal-stem-cells-16342.md)
- [Large-scale and innervated functional human gut tissues for transplantation via transient spheroid confinement](https://library.globalcastmd.com/watch/large-scale-and-innervated-functional-human-gut-tissues-for-transplantation-via-16344) — article · [machine version](https://library.globalcastmd.com/watch/large-scale-and-innervated-functional-human-gut-tissues-for-transplantation-via-16344.md)
- [Engineering Large-Scale and Innervated Functional Human Gut for Transplantation](https://library.globalcastmd.com/watch/engineering-large-scale-and-innervated-functional-human-gut-for-transplantation-16492) — article · [machine version](https://library.globalcastmd.com/watch/engineering-large-scale-and-innervated-functional-human-gut-for-transplantation-16492.md)
- [Functional human gastrointestinal organoids can be engineered from three primary germ layers derived separately from pluripotent stem cells](https://library.globalcastmd.com/watch/functional-human-gastrointestinal-organoids-can-be-engineered-from-three-primary-16362) — article · [machine version](https://library.globalcastmd.com/watch/functional-human-gastrointestinal-organoids-can-be-engineered-from-three-primary-16362.md)
- [Differentiation of Human Pluripotent Stem Cells into Colonic Organoids via Transient Activation of BMP Signaling.](https://library.globalcastmd.com/watch/differentiation-of-human-pluripotent-stem-cells-into-colonic-organoids-via-trans-16384) — article · [machine version](https://library.globalcastmd.com/watch/differentiation-of-human-pluripotent-stem-cells-into-colonic-organoids-via-trans-16384.md)
- [An in vivo model of human small intestine using pluripotent stem cells](https://library.globalcastmd.com/watch/an-in-vivo-model-of-human-small-intestine-using-pluripotent-stem-cells-16398) — article · [machine version](https://library.globalcastmd.com/watch/an-in-vivo-model-of-human-small-intestine-using-pluripotent-stem-cells-16398.md)
- [Establishment of Gastrointestinal Epithelial Organoids](https://library.globalcastmd.com/watch/establishment-of-gastrointestinal-epithelial-organoids-16399) — article · [machine version](https://library.globalcastmd.com/watch/establishment-of-gastrointestinal-epithelial-organoids-16399.md)
- [The Basic Helix-Loop-Helix Transcription Factor NEUROG3 Is Required for Development of the Human Endocrine Pancreas](https://library.globalcastmd.com/watch/the-basic-helix-loop-helix-transcription-factor-neurog3-is-required-for-developm-16477) — article · [machine version](https://library.globalcastmd.com/watch/the-basic-helix-loop-helix-transcription-factor-neurog3-is-required-for-developm-16477.md)
- [Co-development of mesoderm and endoderm enables organotypic vascularization in lung and gut organoids](https://library.globalcastmd.com/watch/co-development-of-mesoderm-and-endoderm-enables-organotypic-vascularization-in-l-16347) — article · [machine version](https://library.globalcastmd.com/watch/co-development-of-mesoderm-and-endoderm-enables-organotypic-vascularization-in-l-16347.md)
- [Coordinated differentiation of human intestinal organoids with functional enteric neurons and vasculature](https://library.globalcastmd.com/watch/coordinated-differentiation-of-human-intestinal-organoids-with-functional-enteri-16349) — article · [machine version](https://library.globalcastmd.com/watch/coordinated-differentiation-of-human-intestinal-organoids-with-functional-enteri-16349.md)
- [Engineered human pluripotent-stem-cell-derived intestinal tissues with a functional enteric nervous system](https://library.globalcastmd.com/watch/engineered-human-pluripotent-stem-cell-derived-intestinal-tissues-with-a-functio-16387) — article · [machine version](https://library.globalcastmd.com/watch/engineered-human-pluripotent-stem-cell-derived-intestinal-tissues-with-a-functio-16387.md)
- [Deriving Human Intestinal Organoids with Functional Tissue-Resident Macrophages All From Pluripotent Stem Cells](https://library.globalcastmd.com/watch/deriving-human-intestinal-organoids-with-functional-tissue-resident-macrophages-16350) — article · [machine version](https://library.globalcastmd.com/watch/deriving-human-intestinal-organoids-with-functional-tissue-resident-macrophages-16350.md)
- [In vivo development of immune tissue in human intestinal organoids transplanted into humanized mice](https://library.globalcastmd.com/watch/in-vivo-development-of-immune-tissue-in-human-intestinal-organoids-transplanted-16358) — article · [machine version](https://library.globalcastmd.com/watch/in-vivo-development-of-immune-tissue-in-human-intestinal-organoids-transplanted-16358.md)
- [Development of functional resident macrophages in human pluripotent stem cell-derived colonic organoids and human fetal colon](https://library.globalcastmd.com/watch/development-of-functional-resident-macrophages-in-human-pluripotent-stem-cell-de-16419) — article · [machine version](https://library.globalcastmd.com/watch/development-of-functional-resident-macrophages-in-human-pluripotent-stem-cell-de-16419.md)

### Organoid Maturation & Function
- [Promoting Human Intestinal Organoid Formation and Stimulation Using Piezoelectric Nanofiber Matrices](https://library.globalcastmd.com/watch/promoting-human-intestinal-organoid-formation-and-stimulation-using-piezoelectri-16346) — article · [machine version](https://library.globalcastmd.com/watch/promoting-human-intestinal-organoid-formation-and-stimulation-using-piezoelectri-16346.md)
- [Mechanical stimulation promotes human intestinal villus morphogenesis in vivo](https://library.globalcastmd.com/watch/mechanical-stimulation-promotes-human-intestinal-villus-morphogenesis-in-vivo-16354) — article · [machine version](https://library.globalcastmd.com/watch/mechanical-stimulation-promotes-human-intestinal-villus-morphogenesis-in-vivo-16354.md)
- [Mechanically induced development and maturation of human intestinal organoids in vivo](https://library.globalcastmd.com/watch/mechanically-induced-development-and-maturation-of-human-intestinal-organoids-in-16378) — article · [machine version](https://library.globalcastmd.com/watch/mechanically-induced-development-and-maturation-of-human-intestinal-organoids-in-16378.md)
- [Suspension culture promotes serosal mesothelial development in human intestinal organoids](https://library.globalcastmd.com/watch/suspension-culture-promotes-serosal-mesothelial-development-in-human-intestinal-16361) — article · [machine version](https://library.globalcastmd.com/watch/suspension-culture-promotes-serosal-mesothelial-development-in-human-intestinal-16361.md)
- [Mesenchymal WNT2B is required for the development and function of the human intestine](https://library.globalcastmd.com/watch/mesenchymal-wnt2b-is-required-for-the-development-and-function-of-the-human-inte-16491) — article · [machine version](https://library.globalcastmd.com/watch/mesenchymal-wnt2b-is-required-for-the-development-and-function-of-the-human-inte-16491.md)
- [WNT2B Deficiency Causes Increased Susceptibility to Colitis in Mice and Impairs Intestinal Epithelial Development in Humans](https://library.globalcastmd.com/watch/wnt2b-deficiency-causes-increased-susceptibility-to-colitis-in-mice-and-impairs-16496) — article · [machine version](https://library.globalcastmd.com/watch/wnt2b-deficiency-causes-increased-susceptibility-to-colitis-in-mice-and-impairs-16496.md)
- [Ontogeny and function of the circadian clock in intestinal organoids](https://library.globalcastmd.com/watch/ontogeny-and-function-of-the-circadian-clock-in-intestinal-organoids-16363) — article · [machine version](https://library.globalcastmd.com/watch/ontogeny-and-function-of-the-circadian-clock-in-intestinal-organoids-16363.md)
- [Drivers of transcriptional variance in human intestinal epithelial organoids](https://library.globalcastmd.com/watch/drivers-of-transcriptional-variance-in-human-intestinal-epithelial-organoids-16364) — article · [machine version](https://library.globalcastmd.com/watch/drivers-of-transcriptional-variance-in-human-intestinal-epithelial-organoids-16364.md)
- [Enteroendocrine cells couple nutrient sensing to nutrient absorption by regulating ion transport](https://library.globalcastmd.com/watch/enteroendocrine-cells-couple-nutrient-sensing-to-nutrient-absorption-by-regulati-16369) — article · [machine version](https://library.globalcastmd.com/watch/enteroendocrine-cells-couple-nutrient-sensing-to-nutrient-absorption-by-regulati-16369.md)
- [Deriving functional human enteroendocrine cells from pluripotent stem cells](https://library.globalcastmd.com/watch/deriving-functional-human-enteroendocrine-cells-from-pluripotent-stem-cells-16379) — article · [machine version](https://library.globalcastmd.com/watch/deriving-functional-human-enteroendocrine-cells-from-pluripotent-stem-cells-16379.md)
- [Transcriptome-wide Analysis Reveals Hallmarks of Human Intestine Development and Maturation In Vitro and In Vivo](https://library.globalcastmd.com/watch/transcriptome-wide-analysis-reveals-hallmarks-of-human-intestine-development-and-16393) — article · [machine version](https://library.globalcastmd.com/watch/transcriptome-wide-analysis-reveals-hallmarks-of-human-intestine-development-and-16393.md)

### Transplantation & In Vivo Models
- [Transplanted human intestinal organoids: a resource for modeling human intestinal development](https://library.globalcastmd.com/watch/transplanted-human-intestinal-organoids-a-resource-for-modeling-human-intestinal-16357) — article · [machine version](https://library.globalcastmd.com/watch/transplanted-human-intestinal-organoids-a-resource-for-modeling-human-intestinal-16357.md)
- [Evaluation of transplantation sites for human intestinal organoids](https://library.globalcastmd.com/watch/evaluation-of-transplantation-sites-for-human-intestinal-organoids-16370) — article · [machine version](https://library.globalcastmd.com/watch/evaluation-of-transplantation-sites-for-human-intestinal-organoids-16370.md)
- [In Vivo Human PSC-Derived Intestinal Organoids to Study Stem Cell Maintenance](https://library.globalcastmd.com/watch/in-vivo-human-psc-derived-intestinal-organoids-to-study-stem-cell-maintenance-16371) — article · [machine version](https://library.globalcastmd.com/watch/in-vivo-human-psc-derived-intestinal-organoids-to-study-stem-cell-maintenance-16371.md)
- [Transplantation of human intestinal organoids into the mouse mesentery: A more physiologic and anatomic engraftment site.](https://library.globalcastmd.com/watch/transplantation-of-human-intestinal-organoids-into-the-mouse-mesentery-a-more-ph-16380) — article · [machine version](https://library.globalcastmd.com/watch/transplantation-of-human-intestinal-organoids-into-the-mouse-mesentery-a-more-ph-16380.md)
- [In Vivo Model of Small Intestine](https://library.globalcastmd.com/watch/in-vivo-model-of-small-intestine-16385) — article · [machine version](https://library.globalcastmd.com/watch/in-vivo-model-of-small-intestine-16385.md)
- [Intravenous Tomato Lectin Injection to Assess Functional Vasculature](https://library.globalcastmd.com/watch/intravenous-tomato-lectin-injection-to-assess-functional-vasculature-16390) — article · [machine version](https://library.globalcastmd.com/watch/intravenous-tomato-lectin-injection-to-assess-functional-vasculature-16390.md)
- [In vivo Fluorescein Isothiocyanate-dextran (FD4) Permeability Assay](https://library.globalcastmd.com/watch/in-vivo-fluorescein-isothiocyanate-dextran-permeability-assay-16391) — article · [machine version](https://library.globalcastmd.com/watch/in-vivo-fluorescein-isothiocyanate-dextran-permeability-assay-16391.md)
- [Erratum to: In Vivo Model of Small Intestine](https://library.globalcastmd.com/watch/erratum-to-in-vivo-model-of-small-intestine-16464) — article · [machine version](https://library.globalcastmd.com/watch/erratum-to-in-vivo-model-of-small-intestine-16464.md)

### Clinical Translation & Applications
- [Human pluripotent stem cell-derived organoids repair damaged bowel in vivo](https://library.globalcastmd.com/watch/human-pluripotent-stem-cell-derived-organoids-repair-damaged-bowel-in-vivo-16353) — article · [machine version](https://library.globalcastmd.com/watch/human-pluripotent-stem-cell-derived-organoids-repair-damaged-bowel-in-vivo-16353.md)
- [Intestinal organoids: roadmap to the clinic](https://library.globalcastmd.com/watch/intestinal-organoids-roadmap-to-the-clinic-16365) — article · [machine version](https://library.globalcastmd.com/watch/intestinal-organoids-roadmap-to-the-clinic-16365.md)
- [Gastrointestinal organoids: a next-generation tool for modeling human development.](https://library.globalcastmd.com/watch/gastrointestinal-organoids-a-next-generation-tool-for-modeling-human-development-16372) — article · [machine version](https://library.globalcastmd.com/watch/gastrointestinal-organoids-a-next-generation-tool-for-modeling-human-development-16372.md)
- [Organoid Center Strategies for Accelerating Clinical Translation.](https://library.globalcastmd.com/watch/organoid-center-strategies-for-accelerating-clinical-translation-16459) — article · [machine version](https://library.globalcastmd.com/watch/organoid-center-strategies-for-accelerating-clinical-translation-16459.md)
- [Autologous Organoid-T Cell Co-Culture Platform for Modeling of Immune-Mediated Drug-Induced Liver Injury.](https://library.globalcastmd.com/watch/autologous-organoid-t-cell-co-culture-platform-for-modeling-of-immune-mediated-d-16409) — article · [machine version](https://library.globalcastmd.com/watch/autologous-organoid-t-cell-co-culture-platform-for-modeling-of-immune-mediated-d-16409.md)

### Biomaterials & Scaffolds
- [Nonadhesive Alginate Hydrogels Support Growth of Pluripotent Stem Cell-Derived Intestinal Organoids.](https://library.globalcastmd.com/watch/nonadhesive-alginate-hydrogels-support-growth-of-pluripotent-stem-cell-derived-i-16376) — article · [machine version](https://library.globalcastmd.com/watch/nonadhesive-alginate-hydrogels-support-growth-of-pluripotent-stem-cell-derived-i-16376.md)
- [Thermal Annealing Enhances Piezoelectricity and Regenerative Potential of PVDF-TrFE Nanofiber Scaffolds](https://library.globalcastmd.com/watch/thermal-annealing-enhances-piezoelectricity-and-regenerative-potential-of-pvdf-t-16411) — article · [machine version](https://library.globalcastmd.com/watch/thermal-annealing-enhances-piezoelectricity-and-regenerative-potential-of-pvdf-t-16411.md)
- [Synthetic hydrogel substrate for human induced pluripotent stem cell definitive endoderm differentiation](https://library.globalcastmd.com/watch/synthetic-hydrogel-substrate-for-human-induced-pluripotent-stem-cell-definitive-16414) — article · [machine version](https://library.globalcastmd.com/watch/synthetic-hydrogel-substrate-for-human-induced-pluripotent-stem-cell-definitive-16414.md)
- [Enhanced Piezoelectric Performance of PVDF-TrFE Nanofibers through Annealing for Tissue Engineering Applications](https://library.globalcastmd.com/watch/enhanced-piezoelectric-performance-of-pvdf-trfe-nanofibers-through-annealing-for-16514) — article · [machine version](https://library.globalcastmd.com/watch/enhanced-piezoelectric-performance-of-pvdf-trfe-nanofibers-through-annealing-for-16514.md)

### Disease Modeling
- [Patient personalized translational tools in cystic fibrosis to transform data from bench to bed-side and back](https://library.globalcastmd.com/watch/patient-personalized-translational-tools-in-cystic-fibrosis-to-transform-data-fr-16366) — article · [machine version](https://library.globalcastmd.com/watch/patient-personalized-translational-tools-in-cystic-fibrosis-to-transform-data-fr-16366.md)
- [Tissue Responses to Shiga Toxin in Human Intestinal Organoids](https://library.globalcastmd.com/watch/tissue-responses-to-shiga-toxin-in-human-intestinal-organoids-16373) — article · [machine version](https://library.globalcastmd.com/watch/tissue-responses-to-shiga-toxin-in-human-intestinal-organoids-16373.md)
- [IL-13-induced intestinal secretory epithelial cell antigen passages are required for IgE-mediated food-induced anaphylaxis](https://library.globalcastmd.com/watch/il-13-induced-intestinal-secretory-epithelial-cell-antigen-passages-are-required-16374) — article · [machine version](https://library.globalcastmd.com/watch/il-13-induced-intestinal-secretory-epithelial-cell-antigen-passages-are-required-16374.md)
- [Guanylate cyclase 2C agonism corrects CFTR mutants](https://library.globalcastmd.com/watch/guanylate-cyclase-2c-agonism-corrects-cftr-mutants-16382) — article · [machine version](https://library.globalcastmd.com/watch/guanylate-cyclase-2c-agonism-corrects-cftr-mutants-16382.md)
- [Drug-induced secretory diarrhea: A role for CFTR.](https://library.globalcastmd.com/watch/drug-induced-secretory-diarrhea-a-role-for-cftr-16392) — article · [machine version](https://library.globalcastmd.com/watch/drug-induced-secretory-diarrhea-a-role-for-cftr-16392.md)

## Statements
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