Collection
Hepatobiliary & Pancreatic Oncology
Educational content from recorded physician discussions — not medical advice. Always talk to your child's care team about your child's situation.
Content of this collection
Hepatocellular Neoplasms1 item
Histologic type predicts disparate outcomes in pediatric hepatocellular neoplasms: A Pediatric Surgical Oncology Research Collaborative study
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Hepatocellular carcinoma (HCC) is a rare cancer in children, with various histologic subtypes and a paucity of data to guide clinical management and predict prognosis. A multi-institutional review of children with hepatocellular neoplasms w
article · Oct 2026
Hepatoblastoma1 item
Characteristics of Transfusion and Association With Oncologic Outcomes in Hepatoblastoma Resection
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Stephanie F Polites, Jennifer H Aldrink, Timothy B Lautz, Robert A Vierkant, Mecklin V Ragan, Audra Reiter, Stephanie Y Chen, Eugene S Kim, Hannah N Rinehardt, Marcus M Malek, Andrew M Fleming, Andrew J Murphy, Jonathan P Roach, Sridharan R
video1:10 · Apr 2026
Undifferentiated Embryonal Sarcoma1 item
Management of undifferentiated embryonal sarcoma of the liver: A Pediatric Surgical Oncology Research Collaborative study
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Background: Undifferentiated embryonal sarcoma of the liver (UESL) is a rare tumor for which there are few evidence-based guidelines. The aim of this study was to define current management strategies and outcomes for these patients using a
article · Oct 2026
Pancreaticoduodenectomy for the treatment of pancreatic neoplasms in children: A Pediatric Surgical Oncology Research Collaborative study
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This is the largest series of pediatric PD patients. PD is curative for SPN and benign neoplasms. Pancreatic insufficiency is the most common postoperative complication. Outcome is primarily associated with histology.
article · Oct 2026
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Characteristics of Transfusion and Association With Oncologic Outcomes in Hepatoblastoma Resection
It is not uncommon for a patient with hepatoblastoma to need a transfusion during resection
Host summaryJill Knepprath summarizing a resource — not the host's own clinical position0:00 ↗
The study was multi-institutional and published in Pediatric Blood and Cancer in 2025
Host summaryJill Knepprath summarizing a resource — not the host's own clinical position0:13 ↗
The study examined how intraoperative transfusion may affect recurrence and survival in hepatoblastoma resection patients
Host summaryJill Knepprath summarizing a resource — not the host's own clinical position0:19 ↗
Of those transfused, the majority received red blood cells
Host summaryJill Knepprath summarizing a resource — not the host's own clinical position0:25 ↗
Only 11% of transfused patients received platelets
Host summaryJill Knepprath summarizing a resource — not the host's own clinical position0:25 ↗
Intraoperative blood transfusions had no effect on recurrence
Host summaryJill Knepprath summarizing a resource — not the host's own clinical position0:32 ↗
Intraoperative blood transfusions were associated with increased death
Host summaryJill Knepprath summarizing a resource — not the host's own clinical position0:32 ↗
There were instances of unnecessary blood transfusions
Host summaryJill Knepprath summarizing a resource — not the host's own clinical position0:39 ↗
Patients who were transfused had higher post-op hemoglobin
Host summaryJill Knepprath summarizing a resource — not the host's own clinical position0:43 ↗
Transfused patients still required more plasma and platelets postoperatively
Host summaryJill Knepprath summarizing a resource — not the host's own clinical position0:43 ↗
The authors think that blood transfusions were mostly red blood cells, and that is what contributed to the post-op coagulopathy
Host summaryJill Knepprath summarizing a resource — not the host's own clinical position0:52 ↗
The authors recommend more careful patient selection for intraoperative transfusions
Host summaryJill Knepprath summarizing a resource — not the host's own clinical position1:00 ↗
The authors recommend a balanced transfusion approach
Host summaryJill Knepprath summarizing a resource — not the host's own clinical position1:00 ↗
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