A multi-institutional comparison of management techniques for infants with giant omphalocele
The study examined 117 infants with giant omphalocele.
Host summaryLizzie Lee summarizing a resource — not the host's own clinical position0:07 ↗
Four treatment approaches were compared: paint-and-wait, operative silos, compression techniques, and Duoderm silo.
Host summaryLizzie Lee summarizing a resource — not the host's own clinical position0:07 ↗
Babies treated with Duoderm silo were most likely to have their abdomen closed in one surgery.
Host summaryLizzie Lee summarizing a resource — not the host's own clinical position0:19 ↗
Approximately 80% of infants treated with Duoderm silo achieved single-stage abdominal closure.
Host summaryLizzie Lee summarizing a resource — not the host's own clinical position0:24 ↗
Some babies treated with operative silos achieved closure sooner than other methods.
Host summaryLizzie Lee summarizing a resource — not the host's own clinical position0:25 ↗
The overall chance of complications was similar across all four treatment methods.
Host summaryLizzie Lee summarizing a resource — not the host's own clinical position0:25 ↗
Almost half of the infants required six months or more before complete abdominal closure could be achieved.
Host summaryLizzie Lee summarizing a resource — not the host's own clinical position0:32 ↗
There is no one-size-fits-all treatment for giant omphalocele.
Host summaryLizzie Lee summarizing a resource — not the host's own clinical position0:38 ↗
Duoderm silos may be a particularly good option when the goal is single-stage abdominal closure.
Host summaryLizzie Lee summarizing a resource — not the host's own clinical position0:38 ↗
Tricks - Omphalocele - Approach & Component Separation For Suture Closure &...
In patients without pulmonary hypoplasia or bad heart problems, first choice is to try early coverage because it is quicker and easier.
opinionBob Langer0:51 ↗
For patients with pulmonary hypoplasia, bad hearts, prematurity, or where the omphalocele is too big and there isn't enough skin to get over, the escharotic technique is used.
clinicalBob Langer1:05 ↗
Silver sulfadiazine (Flamazine in Canada) has been used for many years for omphalocele escharization, as taught by Sigy Ein.
clinicalBob Langer1:09 ↗
Silver-impregnated sponges offer the same advantage as Silvadene but are less messy and don't require painting.
clinicalBob Langer1:44 ↗
Silver Aquacel stuck to the omphalocele sac and became incorporated, failing to fall off as expected once it hardened underneath.
clinicalTodd Ponsky1:54 ↗
Component separation requires going up every day to adjust the compression, which is work-intensive.
clinicalBob Langer5:12 ↗
The most difficult cases are patients with pulmonary hypoplasia or bad hearts where intra-abdominal pressure cannot be safely increased.
clinicalBob Langer5:12 ↗
The objectives of component separation are to minimize postoperative risk of abdominal hypertension and compartment syndrome, increase abdominal capacity at closure, facilitate anatomically definitive midline closure regarding rectus muscles, and limit evisceration and incisional hernias.
Host summaryThe host summarizing a resource — not the host's own clinical position6:19 ↗
The case presented was a 28-week gestation, 1,130g premature female with giant omphalocele including the liver, identified by prenatal ultrasound.
Host summaryThe host summarizing a resource — not the host's own clinical position6:42 ↗
After 10 days of manipulation with the Duoderm silo, the peritoneal sac was still covered, thick, and manageable.
Host summaryThe host summarizing a resource — not the host's own clinical position7:12 ↗
The incision is made 0.5 to 1 centimeter outside the semilunar line, with dissection of the lateral fascia towards the external oblique.
Host summaryThe host summarizing a resource — not the host's own clinical position7:57 ↗
By dissecting the fascia to the mid-axillary line, you can gain between 2 and 4 centimeters of advancement.
Host summaryThe host summarizing a resource — not the host's own clinical position8:26 ↗
This case represents the probable smallest patient with lowest weight and giant omphalocele treated with Abello method and component separation for definitive anatomic closure without evisceration.
Host summaryThe host summarizing a resource — not the host's own clinical position10:19 ↗
Concern exists about whether abdominal wall musculature after component separation in a 1.3kg infant will function normally at 20 years of age.
opinionBob Langer11:41 ↗
Using an absorbable patch leaves the abdominal wall musculature intact, and as the child grows, the patch becomes a smaller percentage of the abdominal wall area.
clinicalBob Langer12:00 ↗
Surgisis was used for a long time but had many recurrences; now Strattice is used with better results.
clinicalBob Langer12:00 ↗
Many omphaloceles have defects that go right up to the costal margin, making it difficult to close that area even with component separation.
clinicalBob Langer12:36 ↗
Often the lower part of the defect is closed primarily, but a patch is needed along the costal margin.
clinicalBob Langer12:50 ↗
Component separation dissection to the mid-axillary line is necessary to adequately mobilize tissue and achieve closure.
clinicalTodd Ponsky13:20 ↗
Six-ply Surgisis with 22 tension lines works better, allowing tension on the patch while bringing the fascia together.
clinicalTodd Ponsky13:31 ↗
Dr. Abello has long-term follow-up with the Duoderm technique showing all patients healed well without problems.
Host summaryThe host summarizing the discussion — not the host's own clinical position14:07 ↗