Vagus Nerve Stimulation for Electrographic Status Epilepticus in Slow-Wave Sleep
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Read the article on pubmed.ncbi.nlm.nih.gov ↗Article · Mar 2016 · 1 min read
In brief
In brief
This case report demonstrates successful treatment of drug-resistant electrographic status epilepticus in slow-wave sleep (ESES) using vagus nerve stimulation in a 12-year-old patient. Following VNS implantation, the patient achieved seizure freedom for over one year, resolution of ESES pattern on EEG, and significant cognitive improvement.
Written by the GCMD Library team from the article.
Statements in this article
Electrographic status epilepticus in slow sleep or continuous spike and waves during slow-wave sleep is an epileptic encephalopathy characterized by seizures, neurocognitive regression, and significant activation of epileptiform discharges during nonrapid eye movement sleep.
There is no consensus on the diagnostic criteria and evidence-based optimal treatment algorithm for children with electrographic status epilepticus in slow sleep.
After vagus nerve stimulator implantation, the patient remained seizure free for more than a year.
Vagus nerve stimulator implantation resolved the electrographic status epilepticus in slow sleep pattern on electroencephalography.
Vagus nerve stimulator implantation resulted in significant cognitive improvement.
Vagus nerve stimulation may be considered for electrographic status epilepticus in slow sleep.