VACTERL Association in Screened Patients with Esophageal Atresia: A Retrospective Cohort Study

jpedsurg.org

Comprehensive VACTERL screening is crucial in children with esophageal atresia (EA), as undetected anomalies can delay diagnosis and treatments for these problems. Screening practices vary widely in the literature, however. This study aimed to assess the proportion of EA patients receiving comprehensive VACTERL screening, examine screening changes over time and determine the prevalence of additional anomalies, VACTERL association and genetic diagnoses.

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Article · Mar 2026 · 1 min read

In brief

This retrospective study evaluates screening practices for VACTERL association in pediatric patients with esophageal atresia, examining how many receive comprehensive multi-system evaluation and tracking changes in clinical protocols over time. The research identifies prevalence rates of associated congenital anomalies and genetic conditions in this population, highlighting gaps in current screening approaches.

Comprehensive VACTERL screening is essential in all esophageal atresia patients to detect associated anomalies early.
Current screening practices for VACTERL components vary widely across institutions, indicating need for standardization.
Undetected VACTERL anomalies can significantly delay diagnosis and appropriate treatment interventions.
The study evaluates screening compliance rates and prevalence of VACTERL association in EA cohorts over time.

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