Utility of Serum Matrix Metalloproteinase-7 as a Biomarker in Cholestatic Infants with Congenital Heart Disease

In brief

This study evaluates MMP-7 as a diagnostic biomarker for biliary atresia in cholestatic infants with congenital heart disease, finding significantly elevated levels in CHD patients, particularly those with pulmonary hypertension. Results suggest MMP-7 may have limited specificity in this population, requiring careful interpretation to avoid unnecessary invasive procedures.

Written by the GCMD Library team from the article.