Paul Wales · Use of a combined transient elastography and biochemical strategy to determine liver fibrosis in pediatric intestinal failure.
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Article1 min read·Published Nov 2026

Use of a combined transient elastography and biochemical strategy to determine liver fibrosis in pediatric intestinal failure.

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Article · Nov 2026 · 1 min read

In brief

In brief

Study develops a combined diagnostic algorithm using transient elastography and biochemical markers to non-invasively detect liver fibrosis in pediatric intestinal failure patients. The approach addresses the clinical challenge of monitoring intestinal failure-associated liver disease without invasive biopsy procedures.

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Paul Wales

Non-invasive monitoring of intestinal failure (IF) associated liver disease is an ongoing challenge in children with IF. Our objective was to develop a combined algorithm of clinical, transient elastography (TE) and biochemical parameters to identify liver fibrosis in this population. A retrospective cohort study of IF patients followed by our intestinal rehabilitation program between November 201…

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