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Article1 min read·Published Jul 2020Older

Reply to Letter to the Editor

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Article · Jul 2020 · 1 min read

In brief

In brief

This correspondence addresses transition zone length differences in Hirschsprung disease patients with and without genetic syndromes. Analysis of 48 patients found no significant difference in transition zone length >5 cm between syndromic (30%) and nonsyndromic (21%) cases.

Written by the GCMD Library team from the article.

Many thanks to Dr. Santos-Jasso for his Letter to the Editor in relation to our article. There were 10 syndromic patients in our series (trisomy 21 [n=3], congenital central hypoventilation syndrome [n=3], Mowat–Wilson syndrome [n=1], Jacobsen syndrome [n=1], Emmanuel syndrome [n=1], trisomy 8 [n=1]). Overall, 3/10 (30%) patients had a TZ length >5 cm compared with 8/38 (21%) in the nonsyndromic cases (p = 0.67), and therefore no statistically significant difference was observed between these groups.

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