Prevalence, Mortality, and Associated Anomalies in Esophageal Atresia: A Retrospective Study of Finnish Population Data (2004–2017)

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Introduction The aim of the study was to investigate the prevalence of esophageal atresia (EA), frequency of associated anomalies, and mortality from 2004 to 2017 in the Finnish population. We hypothesized the Spitz classification and the presence of other congenital malformations would predict mortality in patients with EA as well as assumed the survival to be high among patients with EA. Materials and Methods This retrospective, population-based study was based on the registries maintained by THL Finnish Institute for Health and Welfare and Statistics Finland. The cases were identified and classified according to the World Health Organization's International Classification of Diseases and Health Related Problems (ICD) revisions 9 and 10 (ICD-9 and ICD-10) codes and accompanying written diagnoses. Associated anomalies were classified based on the EUROCAT criteria, and minor anomalies were excluded. All statistical tests were performed as a two-sided significance level set at p

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Article · Oct 2024 · 1 min read

In brief

This population-based retrospective study examines 14 years of Finnish registry data to determine the prevalence, mortality rates, and associated congenital anomalies in esophageal atresia patients. The research evaluates whether Spitz classification and presence of other malformations predict mortality outcomes in this neonatal surgical condition.

Finnish population data (2004-2017) confirms high survival rates in esophageal atresia when stratified by Spitz classification.
Presence of congenital malformations significantly predicts mortality risk in EA patients beyond anatomic type alone.
EUROCAT-based classification of major associated anomalies provides standardized framework for EA outcome prediction.
Population-based registry data validates Spitz classification as reliable prognostic tool in contemporary EA management.
Excluding minor anomalies focuses risk stratification on clinically significant comorbidities affecting EA survival.

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