Neonatal diagnosis of biliary atresia: a practical review and update
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Read the article on pubmed.ncbi.nlm.nih.gov ↗Article · Jan 1970 · 1 min read
In brief
In brief
This review addresses the diagnostic challenge of biliary atresia in neonates, emphasizing the critical importance of early detection when jaundice persists beyond 2 weeks. The article covers current imaging modalities, differential diagnoses, and treatment approaches for this leading cause of neonatal cholestasis that can progress to fatal hepatic fibrosis within the first year if untreated.
Written by the GCMD Library team from the article.
Biliary atresia is challenging to diagnose because many of the clinical and imaging features of this condition overlap with those of other causes of cholestasis in newborns. When jaundice persists beyond 2 weeks of age, the neonate should be evaluated for cholestasis, and biliary atresia - the most common cause of neonatal cholestasis - should be considered. It is critical to diagnose biliary atresia early because failure to treat can result in hepatic fibrosis and death in less than 1 year. In this paper, we review the current diagnostic imaging methods, differential considerations and treatment options for biliary atresia.
DOI:10.1007/s00247-021-05148-y