Impact of radiotracer injection latency and seizure duration on subtraction ictal SPECT co-registered to MRI (SISCOM) performance in children.
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Read the article on pubmed.ncbi.nlm.nih.gov ↗Article · Nov 2026 · 1 min read
In brief
In brief
This retrospective study examines how timing factors—radiotracer injection delay and seizure duration after injection—affect SISCOM accuracy in localizing the epileptogenic zone in 113 children with drug-resistant epilepsy who underwent resective surgery. Findings inform optimal imaging protocols for pediatric epilepsy surgery candidates.
Written by the GCMD Library team from the article.
We evaluated the impact of radiotracer injection latency and post-injection seizure duration on subtraction ictal SPECT co-registered to MRI (SISCOM) test performance in identifying the epileptogenic zone (EZ) in children with drug-resistant epilepsy who had undergone a resective epilepsy surgery. SISCOM concordance with the EZ was retrospectively reviewed to evaluate its performance in 113 childr…
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