Hyperoxia During Neonatal Cardiopulmonary Bypass Is Associated With Worse Clinical Outcomes: A Multi-Institutional Study

In brief

This multicenter study of 1,175 neonates undergoing cardiac surgery found significant variation in oxygen management during cardiopulmonary bypass, with arterial oxygen levels above 221 mm Hg associated with increased mortality and major adverse events. No deaths occurred in patients maintained below 200 mm Hg, suggesting potential benefit from avoiding hyperoxia during neonatal bypass.

Written by the GCMD Library team from the article.