Fosphenytoin pre-medication for pediatric extra-operative electrical stimulation brain mapping.
pubmed.ncbi.nlm.nih.gov shows its articles on its own site.
Read the article on pubmed.ncbi.nlm.nih.gov ↗Article · Nov 2026 · 1 min read
In brief
In brief
This study evaluates fosphenytoin pre-medication's impact on after-discharges and seizures during extra-operative electrical stimulation brain mapping in pediatric epilepsy surgery patients. Results inform optimal seizure prophylaxis strategies to improve safety and mapping efficacy in children undergoing functional brain mapping.
Written by the GCMD Library team from the article.
We studied the effect of fosphenytoin (FOS) pre-medication on the incidence and thresholds of after-discharges (ADs), seizures, and functional responses during electrical stimulation mapping (ESM). As individualized by the attending epileptologist, FOS was given intravenously at 2 mg-phenytoin-equivalents (PE)/kg/min or 150 mg-PE/min (whichever slower). Patients who received and did not receive FO…
Educational content from recorded physician discussions — not medical advice. Talk to your (or your child's) care team about your situation.
Article
Pediatric Epilepsy Surgery: The Prognostic Value of Central Nervous System Comorbidities in Patients and their Families.
Francesco T. Mangano · Published Nov 2026
Article
Neuropsychological outcomes after resection of cortical sites with visual naming associated electrocorticographic high-gamma modulation.
Francesco T. Mangano · Published Nov 2026
Article
Programming parameters affecting seizure reduction in responsive neurostimulation patients at a pediatric center.
Francesco T. Mangano · Published Nov 2026
Article
Investigation of bias in an epilepsy machine learning algorithm trained on physician notes.
Francesco T. Mangano · Published Nov 2026
Article
Development of information sharing in language neocortex in childhood-onset drug-resistant epilepsy.
Francesco T. Mangano · Published Nov 2026
Article
Subdural grid and depth electrode monitoring in pediatric patients.
Francesco T. Mangano · Published Nov 2026
Article
Diffusion tensor imaging in children following prenatal myelomeningocele repair and its predictive value for the need and timing of subsequent CSF diversion surgery for hydrocephalus.
Francesco T. Mangano · Published Nov 2026
Article
Empiric Antibiotic Prescription Patterns in Children With Cerebrospinal Fluid Shunt Infection.
Francesco T. Mangano · Published Nov 2026
Article
Pediatric Hydrocephalus and the Primary Care Provider.
Francesco T. Mangano · Published Nov 2026
Article
White matter characteristics in children with cerebral palsy prior to selective dorsal rhizotomy: a multicenter diffusion tensor imaging study.
Francesco T. Mangano · Published Nov 2026
Article
A probabilistic approach for lateralization of seizure onset zone in drug-resistant epilepsy with bilateral cerebral pathology.
Francesco T. Mangano · Published Nov 2026
Article
Posterior Quadrant Disconnection Procedure for Intractable Epilepsy: A Case Series of 5 Young Pediatric Patients.
Francesco T. Mangano · Published Nov 2026