Alexander Bondoc · Extracorporeal Membrane Oxygenation in a Patient with Biliary Atresia: Case and Review of Extracorporeal Life Support Organization Data
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Article1 min read·Published Jan 2018Older

Extracorporeal Membrane Oxygenation in a Patient with Biliary Atresia: Case and Review of Extracorporeal Life Support Organization Data

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Article · Jan 2018 · 1 min read

In brief

In brief

This case report describes the first documented use of pretransplant ECMO in an infant with biliary atresia complicated by portopulmonary hypertension and cardiomyopathy. Combined extracorporeal life support and hepatic dialysis successfully bridged the patient to liver transplantation, demonstrating a novel application of advanced life support in pediatric end-stage liver disease.

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Alexander Bondoc

Biliary atresia is a newborn cholangiopathy that may lead to portopulmonary hypertension and cirrhosis-induced cardiomyopathy while awaiting liver transplantation. Extracorporeal life support and hepatic toxin filtration are life-saving interventions that provide cardiopulmonary support and hepatic dialysis to allow resolution of a child's illness. We utilized a combination of these extreme measures to bridge an infant with biliary atresia to transplantation. We reviewed cases of extracorporeal life support utilization in transplantation recipients in the Extracorporeal Life Support Organization database and determined that ours was the only use of pretransplant extracorporeal life support in biliary atresia.

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