Francesco T. Mangano · Electrical stimulation mapping of language with stereo-EEG.

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Article1 min read·Published Nov 2026

Electrical stimulation mapping of language with stereo-EEG.

Part of Pediatric Epilepsy Surgery 85 items

pubmed.ncbi.nlm.nih.gov

Electrical stimulation mapping of language with stereo-EEG.

Francesco T. Mangano

We prospectively validated stereo-electroencephalography (EEG) electrical stimulation mapping (ESM) of language against a reference standard of meta-analytic functional magnetic resonance imaging (fMRI) framework (Neurosynth). Language ESM was performed using 50 Hz, biphasic, bipolar, stimulation at 1-8 mA, with a picture naming task. Electrode contacts (ECs) were scored as ESM+ if ESM interfered …

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Article · Nov 2026 · 1 min read

In brief

In brief

This study validates stereo-EEG electrical stimulation mapping for language localization in epilepsy surgery candidates using picture naming tasks at 50 Hz stimulation. Results are compared against meta-analytic fMRI data from Neurosynth to establish accuracy of invasive mapping techniques for preserving language function during resection.

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Francesco T. Mangano

We prospectively validated stereo-electroencephalography (EEG) electrical stimulation mapping (ESM) of language against a reference standard of meta-analytic functional magnetic resonance imaging (fMRI) framework (Neurosynth). Language ESM was performed using 50 Hz, biphasic, bipolar, stimulation at 1-8 mA, with a picture naming task. Electrode contacts (ECs) were scored as ESM+ if ESM interfered …

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