Ramy Shaaban · Efficacy and Effectiveness of SARS-CoV-2 Vaccines: A Systematic Review and Meta-Analysis.
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Article1 min read·Published Oct 2026

Efficacy and Effectiveness of SARS-CoV-2 Vaccines: A Systematic Review and Meta-Analysis.

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Article · Oct 2026 · 1 min read

In brief

In brief

This systematic review and meta-analysis evaluates the efficacy and effectiveness of COVID-19 vaccines in preventing mortality and severe disease following first and second doses. The study synthesizes evidence from multiple databases through June 2021 to inform vaccination strategies during the pandemic.

Written by the GCMD Library team from the article.

Ramy Shaaban

The coronavirus disease 2019 (COVID-19) pandemic has threatened global health and prompted the need for mass vaccination. We aimed to assess the efficacy and effectiveness of COVID-19 vaccines to prevent mortality and reduce the risk of developing severe disease after the 1st and 2nd doses. From conception to 28 June 2021, we searched PubMed, Cochrane, EBSCO, Scopus, ProQuest, Web of Science, WHO-…

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