Characterization of the supplementary motor area syndrome and seizure outcome after medial frontal lobe resections in pediatric epilepsy surgery
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Read the article on pubmed.ncbi.nlm.nih.gov ↗Article · Jan 2012 · 1 min read
In brief
In brief
Retrospective study of 39 pediatric patients undergoing medial frontal lobe resection for intractable epilepsy found that 59% developed transient SMA syndrome, with 82% recovering within one month. Lesional cases on preoperative MRI had significantly lower risk of developing SMA syndrome, and most patients achieved favorable seizure control with minimal permanent neurological deficits.
Written by the GCMD Library team from the article.
Statements in this article
Resection of the medial frontal lobe in adults results in supplementary motor area syndrome, a disorder characterized by transient motor impairment.
After resection in the region of the supplementary motor area, 59% of pediatric patients developed postoperative neurological impairment.
Of patients who developed postoperative neurological impairment after medial frontal resection, 74% were identified as having supplementary motor area syndrome.
No neurological impairment was found after medial frontal surgery in 41% of pediatric patients.
Permanent neurological impairment occurred in 15% of patients after medial frontal lobe resection.
The majority of patients (82%) who developed supplementary motor area syndrome had resolution of their symptoms by 1 month postoperatively.
Preoperative magnetic resonance imaging finding of lesional cases was associated with a significantly decreased likelihood of developing supplementary motor area syndrome (P = .02).
Seizure outcome was favorable after medial frontal surgery in most pediatric patients with medically intractable epilepsy.
Surgery for medically intractable epilepsy in the region of the medial frontal cortex is effective and associated with reversible neurological impairment in the majority of pediatric cases.