Biliary atresia: 20–40-year follow-up with native liver in an Italian centre
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In brief
In brief
Italian single-center retrospective study examines 20-40 year outcomes in biliary atresia patients who underwent Kasai portoenterostomy between 1975-1996. Analysis focuses on native liver survival rates and overall survival in patients who avoided transplantation, addressing a gap in long-term European outcome data.
Written by the GCMD Library team from the article.
Introduction
Biliary atresia (BA) represents the leading indication for liver transplantation in childhood. Only few studies reported the outcome of patients who survived more than 20 years on their native liver, and up to date there are no Italian data available. We reported our 40-year single centre experience with long-term follow-up of BA patients.
Materials and methods
All consecutive patients who underwent Kasai portoenterostomy (KPE) for BA managed at our Institution between 1975 and 1996 were retrospectively reviewed. Native liver (NLS) and overall survival (OS) were analyzed with Kaplan-Meyer curves and LogRank test. A p value of