Perineal Disintegration Syndrome (PDS) in Children With Human Immunodeficiency Virus (HIV) Infection: A Scoping Review

jpedsurg.org

Paediatric healthcare for children with HIV involves managing complex challenges, including severe perineal issues that significantly affect their quality of life. We introduce the term “perineal disintegration syndrome” (PDS) to describe conditions characterised by abscesses and various fistulae involving the anus, rectum, urethra, or reproductive tracts. The literature on PDS is limited and lacks a standardised treatment approach and universally accepted terminology. Our proposal for a new term aims to standardise nomenclature and stimulate targeted research to improve management and outcomes for this vulnerable group.

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Article · Jul 2024 · 1 min read

In brief

This scoping review introduces perineal disintegration syndrome (PDS), a newly proposed term for severe perineal complications in HIV-infected children, including abscesses and complex fistulae. The authors highlight gaps in standardized terminology and treatment approaches, advocating for unified nomenclature to advance research and clinical management in this vulnerable population.

PDS describes severe perineal complications in HIV+ children: abscesses and fistulae involving anus, rectum, urethra, or reproductive tracts.
Current literature lacks standardized terminology and treatment protocols for perineal complications in pediatric HIV patients.
Proposed term 'perineal disintegration syndrome' aims to unify nomenclature and drive focused research in this underserved population.
PDS significantly impacts quality of life in children with HIV, requiring specialized multidisciplinary management approaches.
Standardizing terminology is essential for comparative research and developing evidence-based treatment guidelines for pediatric HIV perineal disease.

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