The outcome of real-time evaluation of biliary flow using near-infrared fluorescence cholangiography with Indocyanine green in biliary atresia surgery
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Read the article on jpedsurg.org ↗Article · Sep 2019 · 1 min read
In brief
In brief
Study of 10 biliary atresia patients demonstrates that near-infrared fluorescence cholangiography with indocyanine green successfully visualizes hilar micro-bile ducts during surgery, achieving 80% positive fluorescence detection. Patients receiving NIR-FCG guidance showed significantly improved postoperative jaundice clearance compared to historical controls without fluorescence imaging.
Written by the GCMD Library team from the article.
Background
Indocyanine green (ICG) fluorescence imaging is a promising tool for intraoperative decision-making. The aim of this study was to evaluate the utility of near-infrared fluorescence cholangiography (NIR-FCG) with ICG in primary surgery for biliary atresia (BA).
Methods
We performed NIR-FCG with ICG in 10 BA patients and observed the fluorescence of their hilar micro-bile ducts and hilar exudate in order to assess the appropriate level at which to dissect the hilar fibrous corn. We compared the jaundice outcome of 10 patients using NIR-FCG (Group A) to that of 35 historical patients in whom NIR-FCG had not been used (Group B).
Results
The mean age of patients was 74.8 days. The classification of BA was type I in two cases and type-III in eight cases. NIR-FCG visualized the hilar micro-bile ducts, and the incidence of positive fluorescence was 80%. The ratio of postoperative normalization of hyperbilirubinemia in Group A was significantly higher than that in Group B (1.0 vs. 0.65, p