Primary hyperoxaluria diagnosed after kidney transplant: A review of the literature and case report of aggressive renal replacement therapy and lumasiran to prevent allograft loss

In brief

This case report describes post-transplant diagnosis of primary hyperoxaluria type 1 and successful allograft preservation using intensive dialysis combined with lumasiran therapy. The article reviews diagnostic challenges when hyperoxaluria presents after kidney transplantation and demonstrates how aggressive renal replacement therapy with targeted RNA interference treatment can prevent graft loss from oxalate deposition.

Written by the GCMD Library team from the article.