Alberto Tozzi · Assessment of causality of individual adverse events following immunization (AEFI): a WHO tool for global use.
Article1 min read·Published Oct 2026

Assessment of causality of individual adverse events following immunization (AEFI): a WHO tool for global use.

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Article · Oct 2026 · 1 min read

In brief

In brief

WHO presents a standardized causality assessment tool to help public health programs distinguish vaccine-related adverse events from coincidental illnesses occurring after immunization. The framework addresses the critical challenge of evaluating serious post-vaccination events in childhood immunization programs globally.

Written by the GCMD Library team from the article.

Alberto Tozzi

Serious illnesses or even deaths may rarely occur after childhood vaccinations. Public health programs are faced with great challenges to establish if the events presenting after the administration of a vaccine are due to other conditions, and hence a coincidental presentation, rather than caused by the administered vaccines. Given its priority, the Global Advisory Committee for Vaccine Safety (GA…

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