Alessandro de Alarcon · A multicenter study analyzing the impact of pre-existing comorbidities on laryngotracheal reconstruction (LTR) outcomes.
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Article1 min read·Published Oct 2026

A multicenter study analyzing the impact of pre-existing comorbidities on laryngotracheal reconstruction (LTR) outcomes.

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Article · Oct 2026 · 1 min read

In brief

In brief

Multicenter analysis examining how pre-existing conditions like chronic lung disease, GERD, and prematurity affect laryngotracheal reconstruction success rates. Study addresses single-center limitations by pooling data to identify comorbidity-specific risk factors and validate predictive models for surgical outcomes.

Written by the GCMD Library team from the article.

Alessandro de Alarcon

Comorbidities such as chronic lung disease and gastroesophageal reflux (GERD), prematurity, and numerous other conditions may impact the success of LTR. Single-center studies are limited in terms of patient numbers and may be underpowered. To analyze the impact of specific comorbidities on the operation-specific and overall surgical success of LTR in a large multicenter cohort and validate a predi…

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