StayCurrentMD · Is Preoperative Antimicrobial Prophylaxis Necessary in Testicular Torsion Surgery? Results from the National Surgical Quality Improvement Program Pediatric
Article1 min read·Published Jan 2026

Is Preoperative Antimicrobial Prophylaxis Necessary in Testicular Torsion Surgery? Results from the National Surgical Quality Improvement Program Pediatric

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Article · Jan 2026 · 1 min read

In brief

In brief

This NSQIP-P database study of 614 pediatric patients found no significant difference in surgical site infections, readmissions, or reoperations between testicular torsion surgeries performed with versus without preoperative antibiotic prophylaxis. The findings suggest limited clinical benefit of routine antimicrobial prophylaxis for this low-complication procedure.

  • - Surgical antimicrobial prophylaxis showed no significant benefit in reducing SSI, readmission, or reoperation rates after testicular torsion surgery. - Postoperative complication rates were extremely low in both SAP and non-SAP groups (614 patients, only 1 SSI observed total). - This NSQIP-P analysis suggests routine preoperative antibiotics may be unnecessary for testicular detorsion procedures. - Despite lack of evidence supporting benefit, SAP continues to be administered in over half of testicular torsion cases (52% in this cohort). - Eliminating routine SAP in testicular torsion surgery could reduce antibiotic exposure without compromising patient safety.

Written by the GCMD Library team from the article.

This study aimed to evaluate the impact of surgical antimicrobial prophylaxis (SAP) on testicular torsion surgery (TTS) postoperative outcomes using data from the National Surgical Quality Improvement Program Pediatric (NSQIP-P). Across multiple studies, NSQIP-P has proven increased sensitivity in recording postoperative complications compared with similar databases.The 2021–2023 NSQIP-P participant user and SAP files were queried for all TTSs. Patients with unrecorded SAP administration data (n = 2,725) were excluded. Postoperative events were then compared between subjects who did or did not receive SAP. Primary outcomes included rates of surgical site infection (SSI), 30-day readmission, and 30-day reoperation. SPSS statistical software was used to perform comparative statistical analyses between groups.A total of 614 patients were included in the study and divided into Group 1 (+SAP, n = 322) and Group 2 (−SAP, n = 292). In the +SAP group, there was no observation of SSI, but one case resulted in 30-day readmission and reoperation. Another 30-day readmission and 30-day reoperation were noted, as well. In the −SAP, there was one observation of a deep incisional SSI who was readmitted. There were no 30-day reoperations in this group. There was no statistical significance in outcomes between the two groups.To date, this is the first study assessing the impact of SAP in torsion-reduction surgeries using the NSQIP-P database. There is a low frequency of postoperative complications with this procedure. Our study suggests limited utility of SAP with this surgery despite continued use.

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