StayCurrentMD · A Declining Incidence of Gastroschisis Parallels Trends in Maternal Smoking Rates in the United States
Article1 min read·Published Dec 2025

A Declining Incidence of Gastroschisis Parallels Trends in Maternal Smoking Rates in the United States

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Article · Dec 2025 · 1 min read

In brief

In brief

This epidemiological study examines the correlation between declining maternal smoking rates and gastroschisis incidence in U.S. live births. The research provides population-level evidence supporting smoking cessation as a modifiable risk factor for this congenital abdominal wall defect, with implications for prenatal counseling and public health interventions.

  • - Maternal smoking is an established risk factor for gastroschisis in offspring. - Declining smoking rates among young adults correlate with decreased gastroschisis incidence in U.S. live births. - Public health interventions reducing maternal smoking may lower congenital anomaly rates.

Written by the GCMD Library team from the article.

Previous studies demonstrated that smoking is a risk factor for gastroschisis. Since smoking rates among young adults have declined, we hypothesized that this would be associated with a concurrent decrease in gastroschisis rates among live births in the United States.

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